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Category: Local Partners

Huge news for our friends at Myers Mushrooms

Photo of Eric Myers and his daughter standing in front of a bottling machine.

Myers Mushrooms announced today that their bottling line is fully assembled! In addition to more great mushroom products from Eric and his team, that also means we can make even more LionBerry Restorative Refresher this summer to keep you hydrated. Our founder Bevin Brooks said it best in her comment: “No Sleep till HYDRATION! We […]

All About AgriClusters

What in the world is an AgriCluster? Ultimately, it is a fancy compound word that refers to interconnected agricultural businesses operating within a small radius. Or, as the North American Food Systems Network says: In order to support these AgriClusters, the North American Food Systems Network created the AgriCluster Resilience and Expansion (ACRE) program. ACRE, […]

International Elderberry Symposium

Photo of a presentation booth with one person behind a table and two customers in front.

We had a wonderful time this week at the International Elderberry Symposium in Columbia, Mo.! Thanks to the amazing friends we made there, we will have some big announcements coming soon, so stay tuned! One of those big connections we made was with Elderglen, an Australian company producing elderberry products. We also got to hang […]

Heartland Regional Food Business Center

Thank you to the Heartland Regional Food Business Center for their post about Lionberry on Instagram! The Business Center is an incredible community resource that supports farm and food enterprises as they develop food and markets in the region. You can follow their Instagram page and view the post below. In their own words: “The […]

Local Partner Spotlight: SHoney Farm and Kennel

Photo of Lionberry Refresher bottle in front of a display of creamed honey products.

If you have visited our LionBerry booth at a recent show, you have probably seen bottles of honey from our friends at SHoney Farm and Kennel. Located in Pottawatomie County,  Kenny and Courtney started Shoney in 2021 with a single hive and have now grown into a multi-yard operation where they raise honeybees, harvest honeycomb […]

Local Partner Spotlight: Myers Mushrooms

Bevin Brooks of Lionberry and Eric Myers of Myers Mushrooms sitting and smiling with their arms crossed.

Eric Myers of Myers Mushrooms is one of our biggest small business allies! This commercial mushroom master has shared so much knowledge with us and we even wrangled him for a recent dinner when we were in Wichita for The Women’s Fair.  Myers started his business in El Paso, Texas, in 2015 and eventually moved […]

Local Partner Spotlight: Buehler Farms

Dave Buehler of Buehler Organics

Buehler Farms has been a staple in the local farming community for more than 125 years. Located in Mt. Vernon, Missouri, Buehler Farms is committed to “agroforestry” which they describe as: At Buehler Farms, we approach farming with the belief that healthy land produces healthy plants and elderberry is at the heart of that mission. […]

METABOLIC RECOVERY – The Next Phase of the GLP-1 Conversation: Metabolic Recovery

Lionberry 's Weekly Delusion and Re-illusion Update.

For the last two years, we’ve been talking about GLP-1 drugs.

Ozempic. Wegovy. Zepbound.

They work.

They reduce appetite, improve blood sugar regulation, and are reshaping metabolic health at scale. This is one of the most significant shifts we’ve seen in decades (Wilding et al., 2021).

But a quieter question is starting to emerge:

What happens after?

Because many people eventually discontinue these medications. They’re expensive, often require ongoing use, and studies have shown substantial weight regain can occur after discontinuation of GLP-1 therapies (Wilding et al., 2022).

Not because people failed.

Because the system that was being supported… is no longer being supported.

I believe we’re entering a new phase of this conversation.

Not just weight loss.

Not just appetite suppression.

But metabolic recovery.

What does the body need to help maintain stability after intervention?

The Washington State University elderberry study led by Professor Patrick Solverson and colleagues, published in 2024, caught my attention immediately (Solverson et al., 2024). Last summer, I also had the opportunity to hear the research presented during the International Elderberry Symposium.

As both an elderberry farmer and a value-added product maker, I was excited to see rigorous science emerging around American elderberry — but also genuinely curious why it wasn’t making larger headlines.

Because the findings were interesting.

In the randomized controlled trial, participants consuming 100% American elderberry juice for one week demonstrated:

  • Reduced blood glucose
  • Lower insulin levels
  • Increased fat oxidation
  • Measurable shifts in gut microbiome activity (Solverson et al., 2024)

Not a miracle.

Not hype.

But a signal.

Because the mechanism matters.

One detail that makes American elderberry especially interesting is that its anthocyanin profile appears to differ from many other dark berries.

American elderberry (Sambucus canadensis) contains significant amounts of acylated anthocyanins — particularly acylated cyanidin-based compounds connected to hydroxycinnamic acid groups (Lee & Finn, 2007; Özgen et al., 2010). These acyl groups alter the chemistry and stability of the anthocyanin molecule.

Why does that matter?

Research suggests acylated anthocyanins demonstrate greater resistance to heat, oxidation, light degradation, and digestive breakdown compared to many non-acylated anthocyanins commonly found in fruits such as blackberries and in many European elderberry varieties (Sadilova et al., 2006; Fuleki & Francis, 1968).

That stability may matter biologically because it potentially allows more intact anthocyanin compounds to survive processing, storage, digestion, and interaction with the gut microbiome.

European elderberry (Sambucus nigra) contains a different anthocyanin composition, dominated more heavily by non-acylated cyanidin 3-glucoside and cyanidin 3-sambubioside compounds (Lee & Finn, 2007). Other berries absolutely contain beneficial anthocyanins too — but American elderberry appears to possess a somewhat distinct anthocyanin architecture that researchers are still working to fully understand.

Researchers believe these anthocyanins interact with the gut microbiome, helping generate short-chain fatty acids and downstream metabolites associated with insulin sensitivity, inflammation regulation, and endogenous GLP-1 signaling pathways (Chambers et al., 2018; Solverson et al., 2024).

Not synthetically.

Endogenously.

Through food and the gut microbiome.

To me, this is where the conversation may be heading next.

Not:

“What replaces GLP-1 drugs?”

But:

“What helps support the body alongside them — and after them?”

Or even:

“What supports metabolic health for people who never start them at all?”

For too long, metabolism has been framed as something we “fix.”

I think we’re moving toward something different:

Metabolism as something we support daily — through food, hydration, gut health, and the biological systems we nourish over time.

For the past year, I’ve been quietly studying this space and building around one core idea:

There may be a meaningful role for real functional food in the GLP-1 era — not as a replacement for medicine, but as nutritional support alongside metabolic health journeys.

Not a shortcut.

A system.

We’re still early in this conversation.

But if the last few years were about intervention…

the next few may be about recovery.

Curious what others in food, agriculture, metabolic health, and functional wellness are seeing emerge in this space.

— Bevin Brooks

References

Solverson, P., Teets, C., Rust, B., Johnson, S.A., et al. (2024). A One-Week Elderberry Juice Intervention Augments the Fecal Microbiota and Suggests Improvement in Glucose Tolerance and Fat Oxidation in a Randomized Controlled Trial. Nutrients, 16(20), 3555.

Wilding, J.P.H., Batterham, R.L., Calanna, S., et al. (2021). Once-Weekly Semaglutide in Adults with Overweight or Obesity. New England Journal of Medicine, 384(11), 989–1002.

Wilding, J.P.H., Jacobsen, L.V., le Roux, C.W., et al. (2022). Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension. Diabetes, Obesity and Metabolism, 24(8), 1553–1564.

Lee, J., & Finn, C.E. (2007). Anthocyanins and Other Polyphenolics in American Elderberry (Sambucus canadensis) and European Elderberry (Sambucus nigra) Cultivars. Journal of the Science of Food and Agriculture, 87(14), 2665–2675.

Özgen, M., Scheerens, J.C., Reese, R.N., & Miller, R.A. (2010). Total Phenolic, Anthocyanin Contents and Antioxidant Capacity of Selected Elderberry Accessions. Pharmacognosy Magazine, 6(23), 198–203.

Sadilova, E., Stintzing, F.C., & Carle, R. (2006). Thermal degradation of acylated and nonacylated anthocyanins. Journal of Food Science, 71(8), C504–C512.

Fuleki, T., & Francis, F.J. (1968). Quantitative Methods for Anthocyanins: Stability of Elderberry Pigments. Journal of Food Science, 33(1), 72–79.

Chambers, E.S., Preston, T., Frost, G., & Morrison, D.J. (2018). Role of Gut Microbiota-Generated Short-Chain Fatty Acids in Metabolic and Cardiovascular Health. Current Nutrition Reports, 7, 198–206.